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Would Palladium ever publish a board game based on the Splicers RPG?

they might, if someone pitched it to them. maybe even as a rifter article or something (obviously, they'd need to include a printable board for that to work). i doubt they're going to do it on their own any time soon though.

I could see it as more of a build-your-own-board or tile board-game, like the Space Hulk board-game, so that several scenarios, plus any the owner/ref could come up with.